Friday, May 27

49ers vs Colts Odds, Prediction, Betting Trends for NFL ‘Sunday Night Football’



When the Colts (2-4) travel to face the 49ers (2-3) on “Sunday Night Football” (8:20 pm ET, NBC) in the penultimate game of NFL Week 7, it will be a matchup of two teams trying to get back on the playoff track. Indianapolis, an AFC South wild card last season, has started slowly with a difficult schedule. San Francisco, which had an injury-plagued 2020 after a Super Bowl run last season, wants to play more like 2019.

Indianapolis has victories over Miami and Houston. San Francisco is coming off a break, but has lost three in a row since starting 2-0 with wins over Detroit and Philadelphia. That makes this a key crossroads game.

The Colts will hope Carson Wentz continues to play well, while the 49ers have Jimmy Garoppolo starting again.

Here’s everything you need to know about betting the 49ers against the Colts in week 7, including updated odds, trends and our prediction for “Sunday Night Football.”

49ers vs Colts odds for ‘Sunday Night Football’

  • Spread: 49ers by 4.5
  • Below: 44.5
  • Moneyine: Colts +184, 49ers -220

(betting odds for FanDuel sports betting)

The line has widened in favor of the 49ers after coming close to a field goal earlier in the week with news of better health. The Colts are playing better with their defensive formula and with lots of runs. The 49ers will try to forge that identity again.

49ers vs. Polts all-time series

The Colts lead the series 26-19. They have won four consecutive games since 2005 and five of seven. Before 1995, the 49ers had a five-game winning streak. Before 1969, the Colts had a 13-game winning streak.

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Three trends to know

– 52 percent of spread bettors are on the Colts’ side now that the number has expanded beyond four points for the 49ers.

—72 percent of above / below category bettors like the game to be over, given that offenses are underrated and defenses have been inflated quite a bit based on the past.

—The Colts are 4-6 up and 5-5 against the margin in their last 10 games with the total surpassing in half of those games. The 49ers are 3-7 SU and 3-7 ATS in their last 10, and half of those games are finished as well.

Three things to look at

Who will run for the 49ers?

There won’t be any Lance doing that as a quarterback. Rookie Elijah Mitchell is hoping to get his first shot at rear end duties, but rookie Trey Sermon and the return of JaMycal Hasty are also in the mix. San Francisco’s traditionally strong running offense hasn’t been a big factor this season. They need that to change against Indianapolis to win.

Will Jonathan Taylor stay red hot?

After a slow first three games with controlled use, Taylor has gone berserk in the last three games running and receiving for the Colts. He has 52 touches for 441 yards from the scrimmage and 5 TDs. The 49ers must run effectively and also stop Taylor on the other side.

Deebo vs. Colts High School

Deebo Samuel has been unleashed as a big game weapon as expected for the 49ers with tight end George Kittle on the shelf and wide receiver Brandon Aiyuk still working out of the proverbial doghouse. The Colts come in with a lot of safety health concerns and cornerback and Samuel is a tough cover because he sees passes all over the field from shortstop to safety. Expect to be busy for Jimmy G and host a revolutionary night.

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Statistics that matter

3-2. That’s Kyle Shanahan’s record after a break as 49ers head coach. His father Mike was an expert in preparing his team to play at a high level after a break. This time, the break also allowed the 49ers to be healthier in places and prepare well for the Colts’ offense.

49ers vs Colts prediction

The Colts will come in and play well, as both teams like to lean on the running game and defense. Taylor keeps the Colts in the game as the 49ers try to maximize a young committee. However, it will take some major passes to win this game, and Wentz has limited key weapons relative to Garoppolo with whom to attack San Francisco.

49ers 27, Colts 23




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