Arizona Cardinals vs. Indianapolis Colts NFL Week 16 Odds, Plays & Outlook for December 25, 2021

The Arizona Cardinals (10-4) and the Indianapolis Colts (8-6) will fight in an NFL Week 16 matchup.

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Odds for Cardinals vs. Colts

Arizona and its opponents have surpassed the current total of 49 points in seven of 14 games (50%) this season.
So far this season, 42.9% of Indianapolis games (6/14) have had more points combined than the 49 over / under on Saturday.
Saturday’s total is 6.4 points lower than the two teams’ combined average of 55.4 points per game.
The combined 41.7 points per game that these two squads have allowed this season are 7.3 less than the 49 totals for this tournament.
The overall average for the Cardinals games this season is 48.4, 0.6 points down from the 49 over / under on Saturday.
In 2021, games involving the Colts averaged a total of 47.0 points, 2.0 less than the over / under game in this game.

In Arizona’s 14 games this season, he has nine wins against differential.
The Cardinals have been favored by 1 point or more nine times this season and are 4-5 ATS in those meetings.
Arizona’s games this year have exceeded total points 50% of their chances (seven times in 14 games with total set points).
The Cardinals score 5.6 more points per game (27.0) than the Colts allow (21.4).
When Arizona scores more than 21.4 points, it is 8-2 against the spread and 9-1 overall.
The Cardinals accumulate 376.4 yards per game, 32.7 yards more than the 343.7 that the Colts give per game.
When Arizona accumulates more than 343.7 yards, the team is 7-3 against the spread and 8-2 overall.
The Cardinals have turned the ball around 14 times this season, 17 fewer than the Colts have forced (31).
Click on to SISportsbook and find the bottom line, money line and total for Arizona’s showdown with the Colts.

Indianapolis is 9-5-0 against the spread this year.
The Colts are 5-3 ATS when they are not favorites by 1 point or more this year.
Indianapolis games this season have exceeded 57.1% of their chances (eight times in 14 games with total set points).
The Colts scored 28.4 points per game, 8.1 more than the Cardinals allow (20.3).
When Indianapolis scores more than 20.3 points, it is 9-3 against the spread and 8-4 overall.
The Colts accumulate 38.6 more yards per game (361.4) than the Cardinals give up per game (322.8).
Indianapolis is 7-2 against the spread and 5-4 overall as the team accumulates more than 322.8 yards.
The Colts have 17 awards this season, while the Cardinals have 24 awards.

Arizona has covered the spread twice at home, and is 3-3 overall there this season.
At home, as 1-point or more favorites, the Cardinals have two ATS victories (2-4).
In three of six home games this year, Arizona has exceeded the total.
This season, the Cardinals’ home games are averaging 48.3 points, 0.7 less than the over / under in this meeting (49).
In road games, Indianapolis is 4-2 overall and 5-1 against differential.
The Colts are undefeated ATS (1-0) as losers of 1 point or more on the road.
In four of six road games this year, Indianapolis has exceeded the total.
The Colts’ average total in away games this season is 45.6 points, 3.4 less than the over / under from this meeting (49).

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Eddie is an Australian news reporter with over 9 years in the industry and has published on Forbes and tech crunch.