Thursday, April 18

Cardinals vs. Pirates odds, line, prediction: 2022 MLB picks, April 11 best bets from proven computer model


The St. Louis Cardinals (2-1) host the Pittsburgh Pirates (1-2) on Monday afternoon as these teams wrap up their opening four-game series. The Cardinals won the first two matchups before Pittsburgh pulled out a win in the last game. Right-hander Dakota Hudson is making the start for St. Louis. Meanwhile, Zach Thompson is making the start for Pittsburgh. It’ll be the season debut for both pitchers. 

First pitch is set for 2:15 p.m. ET. Caesars Sportsbook lists St. Louis as the -180 favorite (risk $180 to win $100) on the money line in the latest Cardinals vs. Pirates odds, while Pittsburgh is the +160 underdog. The over-under for total runs scored is eight. Before making any Pirates vs. Cardinals picks, you need to check out the latest MLB predictions and betting advice from the SportsLine Projection Model.

This model, which simulates every game 10,000 times, enters Week 2 of the 2022 season on a 216-181 roll on top-rated MLB money-line picks that dates back to last season, returning over $900 for $100 players. Anyone following it has seen huge returns.

Now, the model has locked in on Cardinals vs. Pirates, and just locked in its picks and MLB predictions. You can visit SportsLine now to see the model’s picks. Here are the MLB odds and trends for Pirates vs. Cardinals:

  • Cardinals vs. Pirates money line: St. Louis -180, Pittsburgh +160
  • Cardinals vs. Pirates run-line: St. Louis -1.5 (+110)
  • Cardinals vs. Pirates over-under: 8 runs
  • STL: Cardinals went 45-36 at home last season 
  • PITT: Pirates were 24-57 on road last season 

Why you should back the Cardinals

Third baseman Nolan Arenado makes solid and constant contact due to his stellar hands. Arenado has natural home-run power and displays great range from third base. Last season, the six-time All-Star hit 34 home runs and batted in 105 runs. He kicked off this season well, holding a batting average of .500 with two home runs and seven RBI thus far. 

First baseman Paul Goldschmidt brings big-time power and run-producing ability. He has a good batting eye but can also play solid defense. Goldschmidt has recorded at least one hit in all three games thus far and has a batting average of .333. Last season, the six-time All-Star racked up 31 home runs and 99 runs batted in. 

Why you should back the Pirates

Left fielder Bryan Reynolds hasn’t had the start he hoped for but is still a terrific player. Reynolds is a switch hitter with excellent bat control. He runs well and has the versatility to play all three outfield positions. Last season he produced a batting average of .302 with 24 home runs and 90 runs batted in.

Third baseman Ke’Bryan Hayes has played fairly well in this series. Hayes has gotten two hits in consecutive games and sits with a batting average of .400. He also plays great defense with his quick reads and lateral quickness. Hayes has a great arm and can any throw across the diamond. 

How to make Pirates vs. Cardinals picks

SportsLine’s model is leaning over on the run total, as the simulation suggests the teams will combine for 8.9 runs. It also says one side of the money line has all the value. You can only get the model’s pick at SportsLine. 

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So who wins Cardinals vs. Pirates? And which side of the money line has all the value? Visit SportsLine now to see which side to jump on, all from the advanced model that has crushed its top-rated MLB picks, and find out.



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