Saturday, October 1

Cardinals vs. Pirates prediction, betting odds for MLB on Friday provides exclusive sports betting content to, including picks, analysis, tools and sportsbook offers to help bettors get in on the action. Please wager responsibly.

The Pittsburgh Pirates take on the St. Louis Cardinals in MLB at PNC Park on Friday. First pitch is at 6:35 p.m. ET.

Roansy Contreras (4-4, 3.40 ERA) will start on the mound for the Pirates, while the Cardinals will counter with Miles Mikolas (11-10, 3.32 ERA).

This betting analysis for Cardinals vs. Pirates, which includes our best bet of the game, is brought to you by DraftKings Sportsbook and powered by Dimers.

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Cardinals vs. Pirates 2022

Game details

  • When: Friday, September 9, 2022
  • Time: 6:35 p.m. ET
  • Where: PNC Park

Betting odds

  • Run line: Pirates +1.5 (+100), Cardinals -1.5 (-115)
  • Moneyline: Pirates +175, Cardinals -200
  • Total: Over/Under 8 (-112/-105)

Odds and lines are best available at time of publishing and subject to change.

DraftKings has an unbeatable promo for St. Louis vs. Pittsburgh, giving new users a $100 bonus just for betting on the game. Click ➡️ here ⬅️ to get started.

Cardinals vs. Pirates betting preview

Using advanced data and machine learning, Dimers has simulated Friday’s Cardinals vs. Pirates game 10,000 times.

Dimers’ independent predictive analytics model, better known as DimersBOT, gives the Cardinals a 63% chance of beating the Pirates.

Meanwhile, according to DimersBOT, the Pirates (+1.5) are a 51% chance of covering the run line. The Over/Under total of 8 runs is a 56% chance of going Over.

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As always, predictions and probabilities are correct at time of publishing and subject to change.

Cardinals vs. Pirates best bet

Our best bet for Cardinals vs. Pirates in MLB on Friday is Over 8 runs (-112).

Click ➡️ here ⬅️ to place a wager with DraftKings Sportsbook.

Our betting advice is based on detailed modeling and betting intelligence to help you make more informed investments.

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Friday’s matchup between the Cardinals and Pirates in MLB at PNC Park is scheduled to start at 6:35 p.m. ET.

The oldest professional sports league in the world is Major League Baseball. The Cardinals and Pirates are among MLB’s 30 teams, with 29 based in the USA and one in Canada.

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