Sunday, December 5

NFL Picks, Week 6 Predictions: Browns Hand First Loss to Cardinals; Chargers, bills keep warm

The NFL season enters Week 6 and there are five matchups between teams with winning records.

1 pm ET features the renewal of the NFC North rivalry between the Packers and the Bears, which will give rookie quarterback Justin Fields his first start in the series. The red-hot Chargers also face the Ravens in a showdown between Justin Herbert and Lamar Jackson.

The 4 pm ET slot also features two exciting games. AFC West upsets Las Vegas and Denver in a battle of teams trying to keep up in the division, and Heisman Trophy winners Kyler Murray and Baker Mayfield square off in a game between the Cardinals and the Browns.

Buffalo closes the week with a trip to Tennessee on Monday Night Football. That’s a full list of potential postseason matchups, and those games won’t be easy to pick.

Every week, Sporting News will pick up games directly. Here’s a look at our seasonal totals:

With that in mind, below are our picks and predictions for week 6:

Bills, Cowboys, Chargers serious contenders; Chiefs, 49ers down for week 6

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NFL predictions for week 6

  • Tampa Bay Buccaneers (-7) at Philadelphia Eagles

Thursday, 8:20 pm, FOX / NFL Network

Remember Tom Brady’s inexplicable loss on “Thursday Night Football” against the Bears last year? Yes, probably him too. The Eagles rank third in the league in passing defense (194.8) and protect the ball well, but Brady will put pressure on them with a high-flying offense.

Choose: Bucaneros 31, Aguilas 21

  • Miami Dolphins (-3.5) vs Jacksonville Jaguars

Sunday, 9:30 am, CBS

The Jaguars will learn of a 20-game losing streak to London. Both defenses allow more than 30 points per game and the Jaguars have the worst turnover differential in the league. If Jacksonville quarterback Trevor Lawrence is going to win his first start, then he might as well be in the most unlikely spot.

Choose: Jaguars 30, Dolphins 27

  • Green Bay Packers (-4.5) at Chicago Bears

Sunday, 1 pm, FOX

Fields will make his first start against the Packers. Aaron Rodgers is 21-5 against the Bears, and that includes four straight wins. If Fields wants to be loved by the fan base, then this is the game to do it. The Bears have a statistical defense in the top 10, but so do the Packers. Some turnovers made up for Green Bay’s slow start on the road.

Choose: Packers 28, Bears 20

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  • Cincinnati Bengals (-3.5) against Detroit Lions

Sunday, 1 pm, FOX

The Lions have lost two games on last-second field goals. The Bengals are 2-2 in four games decided by three points. That Joe Burrow condition (throat contusion) will need to be monitored throughout the week, and Cincinnati should show greater commitment to the running game. Look for the Bengals to win another tight to split their NFC North section of the schedule.

Choose: Bengals 24, Lions 21

  • Houston Texans at Indianapolis Colts (-10)

Sunday, 1 pm, CBS

The Colts are double-digit favorites at home after five consecutive weeks as underdogs. Houston is 3-2 ATS as an underdog this season, and they are trapping the Colts in a short week. This game will be closer than expected.

Choose: Colts 29, Texans 22

  • Los Angeles Rams (-10.5) vs. New York Giants

Sunday, 1 pm, FOX

The Rams are playing an offense that averages the second-most passing yards at 310.2 yards per game. Sean McVay could also put more emphasis on the running game here, especially against a Giants team that is sorting out injuries with star offensive players Daniel Jones, Saquon Barkley and Kenny Golladay.

Choose: Rams 35, Giants 18

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  • Kansas City Chiefs (-6.5) on Washington soccer team

Sunday, 1 pm, CBS

This is supposedly the right game for the Chiefs, but they can’t take it for granted on the road in Washington. The good news is that Washington has allowed 35.3 points per game and generated just two turnovers in the past three weeks. Kansas City remains patient and Patrick Mahomes brings them back to .500.

Choose: Chiefs 34, Washington 24

  • Minnesota Vikings at Carolina Panthers (-1.5)

Sunday, 1 pm, FOX

Which quarterback do you trust the most? Sam Darnold has six TD passes and six interceptions. Kirk Cousins ​​has 10 TDs and two interceptions. Running backs Dalvin Cook and Christian McCaffrey could return for this one, but it all depends on which quarterback can avoid that costly mistake.

Choose: Vikings 25, Panthers 22

  • Los Angeles Chargers at Baltimore Ravens (-3.5)

Sunday, 1 pm, CBS

This is the most exciting game in the opening window, a battle between star quarterback Justin Herbert and Lamar Jackson. It’s an early kick for a West Coast team, and that’s something to keep in mind. But Los Angeles is 3-0 on the road in a fantastic way.

Choose: Chargers 30, Ravens 27

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  • Arizona Cardinals at Cleveland Browns (-2.5)

Sunday, 4:05 pm, FOX

The Cardinals and Browns have elite offenses, and former Oklahoma Heisman winners Kyler Murray and Baker Mayfield will put on a show. What defense can you stop at crucial times? Murray won the last head-to-head meeting in 2019, and the Cardinals won the last four of the series. This is in Cleveland, however, and the Browns knock out the last undefeated team.

Choose: Browns 33, Cardinals 28

  • Las Vegas Raiders at Denver Broncos (-3)

Sunday, 4:25 pm, CBS

The Raiders and Broncos are stuck in two-game slides after 3-0 starts, and this is an important game to keep pace in the AFC West race. The Raiders swept this series last season, and Derek Carr gets the airstrike back on track on the road.

Choose: Raiders 26, Broncos 24

  • Dallas Cowboys (-4) at New England Patriots

Sunday, 4:25 pm, CBS

The Cowboys are starting to overdo it a bit with a balanced offense around Dak Prescott. Dallas has run more than 200 yards in the past two weeks. The Pats rank fifth in the NFL in scoring defense and will try to curb that momentum, but New England will fall to 0-4 in home games this season.

Choose: Cowboys 23, Patriots 20

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  • Seattle Seahawks at Pittsburgh Steelers (-4.5)

Sunday, 8:20 pm, NBC

Geno Smith takes over as the Seahawks’ starter, and it’s a tough task to face a Pittsburgh defense that has increased passing speed in the past two weeks with the return of TJ Watt. The Steelers are back at .500 with another efficient performance from Ben Roethlisberger.

Choose: Steelers 26, Seahawks 18

  • Buffalo Bills (-4.5) at Tennessee Titans

Monday, 8:15 pm, ESPN

The Bills have a case as the best team in soccer, but this is a tough matchup. Remember the legendary stiff arm of Derrick Henry last year? That was in a 42-16 win against Buffalo. Tennessee is still trying to win back Julio Jones, and that could lead to a thrilling shootout in the AFC. We didn’t bet against Josh Allen after he made that mistake last week.

Choose: Bills 35, Titans 31

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