Thursday, October 28

The clock that marks the time of your immune health


The clock that marks the time of your immune health

The clock that marks the time of your immune health

That Artificial intelligence it is going to modify, and in fact it is already modifying, the world as we know it, it is a reality. Deep Learning, Machine Learning… State-of-the-art technology that also finds its way into multiple branches of science and medicine.

In this increasingly technological development of medicine, researchers at the Buck Institute for Research on Aging and Stanford University, in the United States, They have set in motion a clock capable of measuring our immune health.

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iAge is the name they have given to the device.

This watch is capable of measuring the inflammatory burden of aging, in addition to being able to predict multimorbidity, frailty, immune health, cardiovascular aging …

And all, based on the Deep Learning o Deep Learning, a form of Artificial Intelligence.

The PhD David Furman team found that soluble chemokine CXCL9, a protein present in our immune system, specifically in the blood, was able to provide a series of key data to detect early various age-related pathologies.

‘Taking biology into this approach allowed us to identify a number of metrics, including a small immune protein that is involved in chronic systemic age-related inflammation and cardiac aging,’ David Furman, PhD, associate professor at the Buck Institute, director of the 1001 Immunomes Project at Stanford University. School of Medicine and lead author of the study.

This inflammation is associated with multiple diseases related to the aging of our immune system, so by detecting it, its appearance could be predicted.

The light that CXCL9 protein brings to medicine

Before this study it was already known that the CXCL9 protein it was activated for attract lymphocytes to the place in the body where we are suffering from an infection.

Now, in addition, thanks to this research, it has been confirmed that it is also involved in regulating a large number of genes related to inflammation and vascular aging.

“We have shown that the CXCL9 protein upregulates multiple genes involved in inflammation and that it is also involved in cellular senescence, vascular aging, and adverse cardiac remodeling,” Nazish Sayed, MD, PhD, assistant professor of vascular surgery at Stanford Medicine.

Data, through whose analysis, help to understand the moment our immune system goes through.

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This inflammatory load has even been associated with exceptional longevity that have the centenary people, that is to say, those that live more than one hundred years.

A medical and technological advance that overturns the way we understand our aging.

The study, which has been carried out on more than a thousand subjects analyzed, has published its results in the scientific journal Nature Aging.

IAge watch applications

The technological development of Buck Institute for Research on Aging and Stanfor Universityd has as its main application the possibility of detecting the risk of someone developing multiple chronic diseases.

This is achieved by evaluating the cumulative physiological damage that the immune system of the patient in question may suffer.

Body, bone and muscle fragility associated with age is a great headache for people’s health.

The fact that all age-related diseases are associated with a certain chronic systemic inflammation is what allows increasing the effectiveness of this technological development.

One more option to stay ahead of time.


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